anti arginase 1 (Boster Bio)
Boster Bio is a verified supplier 
Boster Bio manufactures this product 
94
Structured Review
Boster Bio
anti arginase 1
Anti Arginase 1, supplied by Boster Bio, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+arginase+1/Anti-ARG1%2FArginase+1+Rabbit+Monoclonal+Antibody/pmc12856188-111-12-15
Average 94 stars, based on 1 article reviews
Anti Arginase 1, supplied by Boster Bio, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+arginase+1/Anti-ARG1%2FArginase+1+Rabbit+Monoclonal+Antibody/pmc12856188-111-12-15
Average 94 stars, based on 1 article reviews
anti arginase 1 - by Bioz Stars,
2026-09
94/100 stars
Images
Related Articles
Membrane:Article Title: Intestinal Akkermansia muciniphila is Beneficial to Functional Recovery Following Ischemic Stroke. Article Snippet: of immune cells in CNS (Erny et al. 2015; Abdel-Haq et al. 2019; Vuong et al. 2020; Ratsika et al. 2021).. In turn, CNS diseases can also influence the homeostasis of gut microbiota (Wang and Kasper 2014; Kim et al. 2020; Margolis et al. 2021).. For example, Alzheimer’s disease (AD) patients exhibit increased abundance of Bacteroidetes but decreased levels of Firmicutes (Vogt et al. 2017; Carranza-Naval et al. 2021), and the dysbiosis of gut microbiota can lead to behavioral deficits as well as exacerbated AD pathologies (Hu et al. 2016; Chen et al. 2022). Incubation:Article Title: Intestinal Akkermansia muciniphila is Beneficial to Functional Recovery Following Ischemic Stroke. Article Snippet: of immune cells in CNS (Erny et al. 2015; Abdel-Haq et al. 2019; Vuong et al. 2020; Ratsika et al. 2021).. In turn, CNS diseases can also influence the homeostasis of gut microbiota (Wang and Kasper 2014; Kim et al. 2020; Margolis et al. 2021).. For example, Alzheimer’s disease (AD) patients exhibit increased abundance of Bacteroidetes but decreased levels of Firmicutes (Vogt et al. 2017; Carranza-Naval et al. 2021), and the dysbiosis of gut microbiota can lead to behavioral deficits as well as exacerbated AD pathologies (Hu et al. 2016; Chen et al. 2022). |
![( A to I ) Serpine1 +/+ and Serpine1 −/− mice were orthotopically implanted with pancreatic cancer cells (7940B), and tumors were collected at day 21. [(A) and (B)] Flow cytometry quantification of frequencies of total T cells (CD45 + CD3 + ) (A) and conventional dendritic cells (CD45 + F4/80 − CD11c + MHCII + ) (B) among live cells in orthotopic tumors. (C) Co-IF staining for <t>Arg1</t> (green), F4/80 (red), and DAPI (blue) in orthotopic tumors, and corresponding quantification ( n = 3 FOV per animal). (D) Quantitative RT-PCR analysis of Arg1 in BMDMs treated with vehicle or recombinant PAI1 (rPAI1) for 20 hours. Each dot represents individual primary BMDM lines. (E) Flow cytometry quantification of frequency of CD8 + T cells (CD45 + CD3 + CD8 + ) among live cells in orthotopic tumors. [(F) and (G)] Flow cytometry quantification of frequencies and absolute numbers of GZMB + CD8 + T cells (F) and Ki67 + CD8 + T cells (G) following a 5-hour ex vivo PMA/ionomycin stimulation of tumor digests. (H) Co-IF staining for GZMB (green), CD8 (red), and DAPI (blue) in orthotopic tumors, and corresponding quantification ( n = 5 FOV per animal). (I) Co-IF staining for Ki67 (red), CD8 (green), and DAPI (blue) in orthotopic tumors, and corresponding quantification ( n = 5 FOV per animal). ( J ) Experimental design for CD8 + T cell depletion. Mice received control immunoglobulin G (IgG) or anti-CD8 antibody twice per week, starting 5 days postimplantation (7940B). Tumors were harvested at day 21. ( K ) Tumor weight of orthotopic tumors with CD8⁺ T cell antibody-mediated depletion. Symbols in (A) to (I) and (K) represent individual mice. Data are means ± SEM. P values were determined by two-tailed unpaired t test [(A), (B), right of (C), (D), (E) to (G), and right of (H)], Mann-Whitney test [left of (C), left of (H), and (I)], and Mann-Whitney test with Holm-Sidak post hoc (K).](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8251/pmc13048251/pmc13048251__sciadv.aea6734-f4.jpg)
![( A ) Experimental outline of murine PDAC model. Plat +/+ and Plat −/− mice were orthotopically implanted with pancreatic cancer cells (7940B), and tumors were collected 21 days postimplantation. ( B ) Tumor weight of orthotopic tumors harvested from Plat +/+ and Plat −/− mice. ( C ) ELISA of tPA in tissue supernatants from pancreata of Plat +/+ mice (no tumor) and orthotopic tumors from Plat +/+ and Plat −/− mice. ( D ) Picrosirius red staining of orthotopic tumors, and corresponding quantification ( n = 5 FOV per animal). ( E ) Co-IF staining for cCasp3 (red), ECAD (green), and DAPI (blue) in orthotopic tumors, and corresponding quantification ( n = 4 FOV per animal). ( F to H ) Flow cytometry quantification of frequencies of total T cells (F), CD8 + T cells (G), and conventional dendritic cells (H) among live cells in orthotopic tumors. ( I ) Co-IF staining for Arg1 (green), F4/80 (red), and DAPI (blue) in orthotopic tumors, and corresponding quantification ( n = 3 FOV per animal). Symbols in (B) to (I) represent individual mice. Data are means ± SEM. P values were determined by Mann-Whitney test [(B) and (F)], two-way ANOVA with Holm-Sidak post hoc (C), and two-tailed unpaired t test [(D), (E), and (G) to (I)].](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8251/pmc13048251/pmc13048251__sciadv.aea6734-f6.jpg)
![( A ) Experimental outline of murine PDAC model. WT, Serpine1 −/− , and Serpine1 −/− ; Plat −/− mice were orthotopically implanted with pancreatic cancer cells (7940B), and tumors were collected 21 days postimplantation. ( B ) Tumor weight of orthotopic tumors harvested from WT, Serpine1 −/− , and Serpine1 −/− ; Plat −/− mice. ( C ) IHC staining for CD8 in orthotopic tumors, and corresponding quantification ( n = 3 FOV per animal). ( D ) Co-IF staining for Arg1 (green), F4/80 (red), and DAPI (blue) in orthotopic tumors, and corresponding quantification ( n = 3 FOV per animal). Symbols in (B) to (D) represent individual mice. Data are means ± SEM. P values were determined by one-way ANOVA with Holm-Sidak post hoc [(B) to (D)]. ( E ) Working model. Left: Hypoxia stabilizes HIF proteins, inducing PAI1 expression in pancreatic CAFs. Although tPA levels are elevated in PDAC, PAI1 predominantly inhibits its activity, thereby suppressing antitumor immunity. Middle: Elimination of stromal PAI1 restores tPA activity, enhancing antitumor CD8 + T cell responses, accompanied by alleviation of immunosuppressive TAM phenotypes and increased dendritic cell (DC) infiltration. Stromal PAI1-driven tumor growth depends on CD8 + T cells. Right: Removal of stromal tPA abolishes residual tPA activity, further promoting an immunosuppressive TME and tumor growth.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_8251/pmc13048251/pmc13048251__sciadv.aea6734-f7.jpg)